The Indo-American relations during the Donald Trump era undertook a noteworthy transformation, from January 20, 2017, to January 20, 2021. Major components of the relationship between Indian Prime Minister Narendra Modi and American President Donald Trump and the implications of their relationship for Pakistan are stated in this research. Throughout Trump's Presidency, there was a fusion of worries and strategic collaborations in Indo-US relations. The American administration recognized and admitted India as a vital player in the Indo-Pacific region to counterbalance China's rising influence there. This was mirrored in the "2+2" dialogues and the "Howdy Modi" event as these events indicated the firming of economic, military, and political assistance. The extending Indo-American cooperation carried serious implications for Pakistan's traditional alliance with the United States. The United States forced Pakistan to address subjects like terrorism and stability of the region and this pressure stressed bilateral ties.